The present study describes the preliminary findings of a research project aiming at creating a knowledge-base for the protection of caves heritage at Rio Vermelho preservation area in the central Brazilian highlands.A GIS-based relief compartment mapping was conducted using readily available data (e.g., satellite images, geological, and cave locat
Effects of gold and copper mining on the structure and diversity of the surrounding plant communities in Northeast Tiger and Leopard National Park
IntroductionNortheast China Mini Bowl Tiger and Leopard National Park is home to the largest and only breeding family of wild tigers and leopards in China.The mining of open-pit gold and copper mines in the core zone might affect the surrounding forest ecosystem and the survival activities of wild tigers and leopards.MethodsIn order to understand t
Canine distemper virus infection leads to an inhibitory phenotype of monocyte-derived dendritic cells in vitro with reduced expression of co-stimulatory molecules and increased interleukin-10 transcription.
Canine distemper virus (CDV) exhibits a profound lymphotropism that causes immunosuppression and increased susceptibility of affected dogs to opportunistic Accessories infections.Similar to human measles virus, CDV is supposed to inhibit terminal differentiation of dendritic cells (DCs), responsible for disturbed repopulation of lymphoid tissues an
Molecular interplay of pro-inflammatory transcription factors and non-coding RNAs in esophageal squamous cell carcinoma
Esophageal squamous cell carcinoma is the sixth most common cancer in the developing world.The aggressive nature of esophageal squamous cell carcinoma, its tendency for relapse, and the poor survival prospects of patients diagnosed at advanced stages, represent a pressing need for the development of new therapies for this disease.Chronic inflammati